Alkermes plc. (ALKS) FY2025 10-K Annual Report

Filed: Feb 25, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

Alkermes plc. (ALKS) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 25, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Alkermes plc. FY2025 10-K Analysis

Business Overview

  • Core business model: Pharmaceutical development and licensing for specialty medicines, with substantial collaboration and royalty revenues from partners Janssen and Biogen
  • Strategic shift: Sale of Athlone manufacturing facility in May 2024 and transition of VUMERITY manufacturing to Biogen's subcontractor completed August 2025
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Management Discussion & Analysis

  • Revenue product sales, net $1,184.6M up $101.1M YoY from $1,083.5M, driven by LYBALVI (+$66.7M) and ARISTADA (+$23.8M) growth
  • Manufacturing and royalty revenues declined $182.8M to $291.3M, mainly from long-acting INVEGA products down $126.9M
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Risk Factors

  • Regulatory risk: potential increased tax liability of ~$70M on $965.7M in cumulative unremitted U.S. earnings upon repatriation subject to foreign tax credits and withholding
  • Macroeconomic threat: $1.525B senior secured term loans due 2031 with interest margins of 1.75%-2.75% increase financing costs and leverage post-Avadel Acquisition
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Alkermes plc. FY2025 Key Financial Metrics
XBRL

Revenue

$1.5B

-5.2% YoY

Net Income

$242M

-34.2% YoY

Operating Margin

17.2%

-980bp YoY

Net Margin

16.4%

-719bp YoY

ROE

13.3%

-1177bp YoY

Total Assets

$2.5B

+21.0% YoY

EPS (Diluted)

$1.43

-34.1% YoY

Operating Cash Flow

$521M

+18.6% YoY

Source: XBRL data from Alkermes plc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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