Arcellx, Inc. (ACLX) FY2025 10-K Annual Report

Filed: Feb 26, 2026
Health Care
Biological Products, (No Diagnostic Substances)SEC EDGAR

Arcellx, Inc. (ACLX) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 26, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

Arcellx, Inc. FY2025 10-K Analysis

Business Overview

  • Core business: Clinical-stage biotech developing novel D-Domain powered CAR-T immunotherapies for cancer and autoimmune diseases
  • New emphasis: ARC-SparX universal CAR-T platform and expanded non-oncology trials including Phase 1 generalized Myasthenia Gravis (gMG) dosing in 2025
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Risk Factors

  • Regulatory risk: Hart-Scott-Rodino Antitrust Act clearance required for Gilead merger, with timing and approval uncertainty risking deal abandonment
  • Macroeconomic risk: Global pandemics and U.S. trade policy changes may disrupt operations and third-party providers critical to business
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Arcellx, Inc. FY2025 Key Financial Metrics
XBRL

Revenue

$22M

-79.4% YoY

Net Income

-$229M

-113.3% YoY

Operating Margin

-1135.6%

-100816bp YoY

Net Margin

-1027.3%

-92780bp YoY

ROE

-56.9%

-3330bp YoY

Total Assets

$604M

-15.1% YoY

EPS (Diluted)

$-4.07

-103.5% YoY

Operating Cash Flow

-$210M

-151.9% YoY

Source: XBRL data from Arcellx, Inc. FY2025 10-K filing on SEC EDGAR. All figures in USD.

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