ACADIA PHARMACEUTICALS INC (ACAD) FY2025 10-K Annual Report

Filed: Feb 26, 2026
Health Care
Pharmaceutical PreparationsSEC EDGAR

ACADIA PHARMACEUTICALS INC (ACAD) 10-K annual report for fiscal year 2025, filed with SEC EDGAR on Feb 26, 2026. This page provides AI-powered analysis including business overview, management discussion & analysis (MD&A), risk factors, and key financial data such as revenue, net income, gross margin, operating margin, and return on equity (ROE) extracted from XBRL.

ACADIA PHARMACEUTICALS INC FY2025 10-K Analysis

Business Overview

  • Core business: biopharmaceutical focus on neurological and rare diseases with $1.07B net sales from NUPLAZID and DAYBUE in 2025, up from $958M in 2024
  • New product launch: DAYBUE STIX powder formulation introduced in Q1 2026 for Rett syndrome, offering dosing flexibility and improved patient experience
+3 more insights

Management Discussion & Analysis

  • Revenue $1,071.5M in 2025 vs $957.8M in 2024, driven by NUPLAZID and DAYBUE sales, up $113.7M YoY
  • Operating loss driven by R&D expenses $328.8M in 2025 vs $303.2M in 2024; gross-to-net adjustments reduced net sales by $20.1M from Medicare rebate revision
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Risk Factors

  • Cybersecurity incident escalation to audit committee requiring coordination among CIDO, Chief Legal Officer, and Senior VP of Finance
  • New CIDO hired August 2025 tasked with integrating cybersecurity risk into overall risk strategy
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ACADIA PHARMACEUTICALS INC FY2025 Key Financial Metrics
XBRL

Revenue

$1.1B

+11.9% YoY

Net Income

$391M

+72.7% YoY

Operating Margin

9.8%

-1431bp YoY

Net Margin

36.5%

+1285bp YoY

ROE

31.9%

+95bp YoY

Total Assets

$1.6B

+31.7% YoY

EPS (Diluted)

$2.30

+69.1% YoY

Operating Cash Flow

$110M

-30.4% YoY

Source: XBRL data from ACADIA PHARMACEUTICALS INC FY2025 10-K filing on SEC EDGAR. All figures in USD.

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